Bioactivity | [Nle8] Somatostatin (1-28) TFA is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) TFA increases the amylase release.[Nle8] Somatostatin (1-28) TFA increases the cyclic AMP in pancreatic acini [1]. |
Sequence | Ser-Ala-Asn-Ser-Asn-Pro-Ala-{Nle}-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (disulfide bridge:Cys17-Cys28) |
Shortening | SANSNPA-{Nle}-APRERKAGCKNFFWKTFTSC (disulfide bridge:Cys17-Cys28) |
Formula | C138H209N41O39S2.xC2HF3O2 |
Molar Mass | 3130.52 (free base) |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Esteve JP, et al. Bimodal regulation of pancreatic exocrine function in vitro by somatostatin-28. Am J Physiol. 1983 Aug;245(2):G208-16. |