PeptideDB

[Nle8] Somatostatin (1-28) (TFA)

CAS: F: C138H209N41O39S2.xC2HF3O2 W: 3130.52 (free base)

Somatostatin (1-28) TFA is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8.Somatos
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity [Nle8] Somatostatin (1-28) TFA is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) TFA increases the amylase release.[Nle8] Somatostatin (1-28) TFA increases the cyclic AMP in pancreatic acini [1].
Sequence Ser-Ala-Asn-Ser-Asn-Pro-Ala-{Nle}-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (disulfide bridge:Cys17-Cys28)
Shortening SANSNPA-{Nle}-APRERKAGCKNFFWKTFTSC (disulfide bridge:Cys17-Cys28)
Formula C138H209N41O39S2.xC2HF3O2
Molar Mass 3130.52 (free base)
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Esteve JP, et al. Bimodal regulation of pancreatic exocrine function in vitro by somatostatin-28. Am J Physiol. 1983 Aug;245(2):G208-16.